East China University of technology researchers use multichannel spectrometer autonomous building, observation of optical signals into a single nanoparticle and single-particle spectroscopy combined with the variety of means of control, successful on-line monitoring into a single growth process of gold, silver and copper nanoparticles, and apply it to the real-time tracking of biological molecules. Relevant outcomes has been Germany the journal of applied chemistry, "hot article" received, will be released in 2012, the first magazine cover page forms.
Article corresponding author is a Professor of East China University dragons yitao, first author Qin Lixia doctoral, Israel participated in the study of Hebrew University of Jerusalem. The study on NSFC major research plan of financing.
Gold, silver, copper and other precious metal nanoparticles with Plasmon resonance scattering nature of this scattering spectrum than the fluorescence intensity is high and stable, has been widely used in areas such as bio-sensing, molecular recognition. At present, the single scattering of Nano-particle levels are still at an emerging stage, its application in the metabolism of living cells in real time monitoring and study physics research.
Prior to this, the team uses a spectrometer platform has been successfully intracellular distribution of NADH to capture live images and applied to the screening of antitumor drugs. Their cooperation with the Shanghai Institute of applied physics, Chinese Academy of Sciences, also achieved innovative results in DNA testing. Currently, the research group is more work in Nano-spectroscopy, molecular level with a view to achieving a single bio-molecular detection of tracking, micro-information for more life activities.
